The main mission of the centre is to promote modern Prague interwar and post-war architecture, residential culture, applied arts and lifestyle, represented in different ways in the two buildings, in close connection with two important villas - Müller and Rothmayer.

The studio of František Bílek is open to visitors in the villa. In part of the building there is a permanent exhibition which, in addition to the original interior furnishings, also presents Bílek's works from his peak creative period.

The national cultural monument was designed by architect Adolf Loos and built for the family of František Müller. It houses a study and documentation centre for researchers. The Raumplan space concept was used in the construction. The interior is in the spirit of modern functionalism and classical English style.

The villa of the architect Otto Rothmayer houses a permanent exhibition The Story of a House and a Family. The exhibition recalls the distinctive style of Otto Rothmayer's architectural work and at the same time seeks to evoke the atmosphere of the living, working and artistic environment that Rothmayer created together with his wife.

We operate a literary museum. We provide protection of museum collections. We carry out scientific research. We acquire, permanently preserve, process and make accessible collections of documents on the development of literature in the Czech lands. We organize and art exhibitions and programs for the public. We offer space rentals.

We take care of collections of Czech art of the 19th, 20th and 21st centuries, a number of public sculptures in Prague, including the sculptures of Charles Bridge. The exhibition programme is oriented towards the presentation of Czech and foreign art of the period and introducing the public to the work of contemporary artists.