Litoměřice Castle is a former Gothic royal castle, which was part of the city walls. It has been protected as a cultural monument since 1964 and is one of the oldest buildings in Litoměřice. The heart of the castle is the wine exposition. There is also an exhibition of Felix Holzmann and an exposition of Litoměřice brewing.

Pátek Castle was originally a summer palace built between 1544 and 1557 by John the Younger of Lobkowitz, one of the richest noblemen in the Czech Kingdom. It is one of the first purely Renaissance buildings in Bohemia. Towards the end of the 17th century it was rebuilt in Baroque style and surrounded by a farmyard.

The fairy tale The Princess with the Golden Star, The Crown Prince and the series Hospital on the Edge of Town were filmed in the castle.