The museum has a permanent exhibition of J.W. Goethe, the geographical development and nature of the region, the history of the Marianske Lazne, balneology and a geographical park in the countryside.

Museum Operations. The permanent exhibition offers an overview of the history and nature of Karlovy Vary with an emphasis on the specifics of the spa town. The museum presents living and non-living nature with reference to ecology, archaeological findings, the development of the region's settlement, the origins of towns and mining activities in the region and more.